Semaglutide is a popular medication for weight loss, originally developed to treat type 2 diabetes. Under brand names like Ozempic and Wegovy, it has gained FDA approval for chronic weight management in adults with obesity or overweight conditions.
If you’re considering semaglutide for weight loss, understanding the proper dosage chart is crucial for safety and effectiveness. This guide covers the recommended dosing schedule, potential side effects, and key considerations.
Semaglutide Weight Loss Dosage Chart
Semaglutide is administered via weekly subcutaneous injections. The dosage is gradually increased to minimize side effects like nausea and gastrointestinal discomfort. Below is the standard Wegovy (semaglutide) weight loss dosage schedule:
| Week | Dosage | Notes |
|---|---|---|
| Weeks 1-4 | 0.25 mg once weekly | Starting dose to help the body adjust |
| Weeks 5-8 | 0.5 mg once weekly | First increase to enhance effects |
| Weeks 9-12 | 1 mg once weekly | Further dose escalation |
| Weeks 13-16 | 1.7 mg once weekly | Nearing the full maintenance dose |
| Week 17+ | 2.4 mg once weekly | Full maintenance dose for weight loss |
Key Notes on Dosage Adjustments
- Stick to the schedule—Rapid increases can worsen side effects.
- If side effects are severe, your doctor may delay dose escalation.
- Do not exceed 2.4 mg/week unless directed by a healthcare provider.
How Does Semaglutide Work for Weight Loss?
Semaglutide is a GLP-1 (glucagon-like peptide-1) receptor agonist, which:
✅ Reduces appetite by acting on hunger signals in the brain.
✅ Slows stomach emptying, helping you feel full longer.
✅ Improves blood sugar control, reducing cravings.
Clinical trials show that patients on semaglutide lose an average of 12-15% of their body weight over 68 weeks when combined with diet and exercise.
Potential Side Effects of Semaglutide
While effective, semaglutide can cause side effects, especially when starting or increasing the dose:
Common Side Effects
- Nausea
- Vomiting
- Diarrhea
- Constipation
- Stomach pain
Less Common but Serious Side Effects
- Pancreatitis (severe abdominal pain)
- Gallbladder issues
- Kidney problems
- Low blood sugar (if combined with other diabetes medications)
Tip: To minimize nausea, eat smaller meals and avoid high-fat foods.
Who Should Avoid Semaglutide?
Semaglutide is not suitable for everyone. Avoid it if you:
❌ Have a personal or family history of medullary thyroid cancer (a rare but serious risk).
❌ Have Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).
❌ Are pregnant or breastfeeding.
❌ Have severe gastrointestinal disease.
Always consult a doctor before starting semaglutide.
How Long Does It Take to See Results?
Weight loss with semaglutide is gradual:
- First 4 weeks: Minimal weight loss (body adjusting).
- Weeks 5-12: Steady weight loss begins (1-2 lbs per week).
- Months 4-6: Maximum effects seen with the full 2.4 mg dose.
Best results come with:
✔ A calorie-controlled diet (high protein, fiber, and hydration).
✔ Regular exercise (even light activity helps).
✔ Consistent weekly injections.
Final Thoughts
Semaglutide (Wegovy) is a powerful tool for weight loss, but success depends on following the correct dosage schedule and making healthy lifestyle changes. Always work with a healthcare provider to monitor progress and adjust treatment as needed.
If you’re struggling with obesity or weight-related health issues, semaglutide could be a game-changer—just ensure you use it safely and effectively.
Would you like a personalized semaglutide plan? Consult your doctor to see if it’s right for you!
Disclaimer: This post is for informational purposes only and does not replace medical advice. Always consult a healthcare professional before starting any medication.
